Understanding Glucophage SR: A Comprehensive Guide

Glucophage SR, also known as Metformin Hydrochloride Sustained Release, is a widely prescribed medication for managing type 2 diabetes. Its unique formulation helps maintain blood sugar levels and provides extended-release benefits to patients. In this detailed guide, we will explore what Glucophage SR is, how it works, its uses, potential side effects, and recommendations for use.

What is Glucophage SR?

Glucophage SR is a prescription medication that belongs to the biguanide class of drugs. It is primarily used to improve blood sugar control in adults with type 2 diabetes. The “SR” stands for sustained release, meaning the medication is designed to gradually release into the bloodstream, providing a prolonged effect compared to immediate-release formulations.

Mechanism of Action

Glucophage SR works by:

– Decreasing glucose production in the liver – Increasing insulin sensitivity in muscle cells – Delaying the absorption of sugar in the intestines

These combined actions help lower blood sugar levels, making it easier for individuals with type 2 diabetes to manage their condition effectively.

Indications for Use

Doctors typically prescribe Glucophage SR for:

– Adults with type 2 diabetes who are unable to control their blood sugar levels through diet and exercise alone – Patients who prefer a once-daily dosing schedule for convenience

It is important to note that Glucophage SR is not intended for use in individuals with type 1 diabetes or diabetic ketoacidosis.

Recommended Dosage and Administration

The typical starting dose for Glucophage SR is 500 mg once daily with the evening meal. Depending on the patient’s response and blood sugar levels, the dose may be gradually increased by 500 mg every one to two weeks. The maximum recommended daily dose is 2000 mg.

Dosage	Administration
500 mg	Once daily with the evening meal
1000 mg	Once daily with the evening meal
2000 mg	Once daily with the evening meal

Potential Side Effects

Like all medications, Glucophage SR can cause side effects. Some common side effects include:

– Nausea – Diarrhea – Stomach pain – Loss of appetite

These effects are often mild and tend to resolve as the body adjusts to the medication. However, if you experience severe side effects such as lactic acidosis, characterized by muscle pain, difficulty breathing, or unusual tiredness, seek medical attention immediately.

Comments from Healthcare Professionals

Dr. Sarah Thompson, an endocrinologist, explains, “Glucophage SR is a cornerstone in the management of type 2 diabetes. Its extended-release formulation is particularly beneficial for patients seeking a simpler dosing regimen.”

Expert Recommendations

– Always take Glucophage SR as prescribed by your healthcare provider. – Combine medication with a balanced diet and regular exercise for optimal results. – Monitor your blood sugar levels regularly to ensure the medication is effectively managing your diabetes.

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Conclusion

Glucophage SR plays a vital role in managing type 2 diabetes, offering a sustained release formulation that improves blood sugar control. By understanding its mechanism, proper usage, and potential side effects, patients can better manage their diabetes and improve their quality of life. For further questions and personalized advice, consult with a healthcare professional.

Sources: – American Diabetes Association – National Institute of Diabetes and Digestive and Kidney Diseases